OVER-EXPRESSION OF CYSTEINE LEUCINE RICH PROTEIN IS RELATED TO SAG RESISTANCE IN CLINICAL ISOLATES OF LEISHMANIA DONOVANI.

Over-Expression of Cysteine Leucine Rich Protein Is Related to SAG Resistance in Clinical Isolates of Leishmania donovani.

BACKGROUND:Resistance emergence against antileishmanial drugs, particularly Sodium Antimony Gluconate (SAG) has severely hampered the therapeutic strategy against visceral leishmaniasis, the mechanism of resistance being indistinguishable.Cysteine leucine rich protein (CLrP), was recognized as one of the overexpressed proteins in resistant isolates

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Indirect establishment increases the chances of in vitro propagation of mosses occurring in the Cerrado - a new method

Abstract The use of micropropagation techniques is crucial for the conservation of endangered moss species and their reestablishment in nature.This study aimed to establish in vitro cultures of gametophyte fragments of ten species of Cerrado mosses.After disinfestation with alcohol and commercial bleach, moss explants were grown in Petri dishes con

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Slovak Criminal Justice and the Philosophy of Its Privatization: An Appropriate Solution of Problems of Slovak Justice in the 21st Century?

The authors of the paper deal with the philosophy of the privatization of elements of criminal justice, which in the last decades influenced the development of criminal justice in European countries, including the Slovak Republic.The philosophy of privatization in relation to criminal justice represents a wider acceptance of the individual interest

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Investigation on the Mechanical Properties and Shape Memory Effect of Landing Buffer Structure Based on NiTi Alloy Printing

Abstract With the deepening of human research on deep space exploration, our research on the soft landing methods of landers has gradually deepened.Adding a buffer and energy-absorbing structure to the leg structure of the lander has become an effective design solution.Based on the energy-absorbing structure of the leg of the interstellar lander, t

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Pengaruh Penambahan Jerami Nangka (Artocarpus heterophyllus Lam) Terhadap Karakteristik Fruit Leather Mangga (Mangifera indica L)

ABSTRAK Penganekaragaman pangan merupakan program kebijakan pemerintah dengan tujuan untuk terus mengembangkan pangan agar dapat memantapkan kemandirian dan penyediaan pangan dengan jenis yang beragam dan kualitas yang makin meningkat, jumlah yang memadai dan tersebar merata sehingga dapat memenuhi kebutuhan pangan dan gizi.Untuk mendukung penganek

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